As I have anticipated last week (have a look here to figure out some of the new therapeutic targets for migraine), the main character of my master thesis in Neurobiology is the kynurenic acid (KYNA), one of the neuroactive compounds produced during the metabolism of tryptophan, an amino acid used in the biosynthesis of proteins.… Continue reading How did I study the effects of KYNA on migraine?
Since last week I started talking about the most common drugs used to treat the migraine symptoms, this week I would like to talk about the new targets that are started to be addressed for the treatment of migraine. As a matter of fact, thanks to the most recent intuitions on the aetiology of migraine,… Continue reading Which are the new therapeutic targets for migraine?
For this week's post I decided it is time to go back to the story of how I ended up doing a PhD in Germany and I will start talking about my Neurobiology master thesis, outlining in the SRF the medical problem that lead researchers, and my lab, working on it. By the beginning of… Continue reading What is migraine?
Today I will talk again about the neuromodulators used by the brain (you can find a quick description of what a neuromodulator is here and a description of serotonin, oxytocin, adrenaline and dopamine by clicking on their names) and I will write about the neuropeptide Y (NPY), the most abundant neuropeptide in the brain that,… Continue reading Do we have an anxiolytic neuromodulator?
This week I will take a break from the “brain facts” category and, consequently, from the description of the different neuromodulators our brain use (you can find a quick description of what a neuromodulator is here and a description of serotonin, oxytocin, adrenaline and dopamine by clicking on their names) to talk about a “news… Continue reading What is the CAR-T therapy?
On this post I will continue writing about neurotransmitters (see this post for a quick explanation of the term neurotransmitter) and today I will focus on dopamine, a neurotransmitter involved in movement, or better, motor control (unfortunately, defects in the dopaminergic systems are well known by Parkinson patients and their families) as well as executive… Continue reading What about the “molecule of motivation”?
Following up on my neuromodulators topic (have a look at my previous posts about serotonin and oxytocin), today I will talk about the “stress” or “fight-or-flight” hormone: adrenaline. Experiencing a stressful event usually triggers the release of adrenaline, the “stress hormone”, that in turn produces well-orchestrated physiological changes. The stress response begins in the brain,… Continue reading What is the “fight-or-flight” response?
Following up on chemical messengers used by the brain and their modulators, today I will talk about oxytocin, the “love molecule”. Oxytocin is a neuromodulator, that is, as I already written on my previous post about serotonin, a molecule able to modulate the transmission of information among neurons. However, oxytocin is also a hormone (basically,… Continue reading What about the love molecule?
Unfortunately, my period of depression is still on and despite few moments of calm and tranquility, as soon as something happens, I fall right back down into it and getting back to a positive view and to quiet seas were to swim happily before finally being able to touch dry land and get out of… Continue reading Which is the “molecule of happiness”?
Another very interesting course that I attended during my first year of Neurobiology Master‘s was the one called “Neurochemistry and Neuropharmacology”. During this course, we finally started studying the different chemicals, called neurotransmitters, produced by neurons in the nervous system. As I have already written in an old post, neurons communicate through electricity and chemical… Continue reading How do benzodiazepines work?